CJC- 1295 Without DAC

CJC-1295 No DAC is a synthetic analog of Growth Hormone Releasing Hormone (GHRH). It is a modified version of the shortest fully functional fragment of GHRH, often referred to as GRF 1-29. The "No DAC" (Drug Affinity Complex) designation indicates that this peptide does not contain the lysine-linker added to increase half-life, allowing for the study of acute, pulsatile signaling.

This compound is intended for in vitro and in vivo laboratory research only, specifically for investigating the pituitary-growth hormone axis.

Research Applications

• GHRH Receptor Agonism: Study of the binding affinity and activation of the GHRH receptor in pituitary cell cultures.

• Pulsatile Hormone Signaling: Investigation of the acute release patterns of endogenous Growth Hormone.

• Structural Stability Studies: Researching how the four amino acid substitutions (at positions 2, 8, 15, and 27) protect the peptide from DPPIV degradation.

• Somatotropic Axis Research: Analysis of the downstream effects of GHRH analogs on IGF-1 production in animal models.

  
  

SOLD FOR RESEARCH PURPOSES ONLY