5-Amino 1MQ

5-Amino-1MQ is an investigational small-molecule compound (often grouped with performance peptides) that acts as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). By blocking NNMT—which is heavily involved in regulating energy metabolism and fat storage—it alters cellular metabolism, increases energy expenditure, and influences NAD+ pathways.  

Primary areas of research include:

• Fat Loss & Obesity: Preclinical studies show it can significantly reduce white adipose tissue mass, decrease fat cell size, and boost resting energy expenditure without altering food intake.  

• Metabolic Health & Type 2 Diabetes: Researched for its potential to improve insulin sensitivity, lower plasma cholesterol levels, and combat metabolic dysfunction associated with high-fat diets.  

• Muscle Strength and Sarcopenia: Animal studies indicate it can enhance grip strength, improve muscle quality by reducing ectopic fat deposits in muscle tissue, and support muscle stem cell repair.  

• NAD+ and Cellular Longevity: Because NNMT degradation impacts NAD+ synthesis precursors, 5-Amino-1MQ is studied for its capacity to restore cellular NAD+ levels, supporting mitochondrial health and pathways tied to sirtuins (longevity genes). 

FOR RESEARCH PURPOSES ONLY